RegenerativeIn Stock
GHK-Cu
Copper Tripeptide Complex
100mg · Lyophilised Powder
$119.00
GHK-Cu (Glycine-Histidine-Lysine-Copper) is a naturally occurring tripeptide with a high affinity for copper ions. Research has documented its involvement in tissue remodeling, antioxidant activity, and gene expression modulation.
Form
Lyophilised Powder
Purity
≥99% (HPLC)
Storage
2–8°C / 36–46°F
Use
Research Only
1
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Research Overview
GHK-Cu (Glycyl-L-Histidyl-L-Lysine:Copper²⁺) is a naturally occurring human plasma copper-binding peptide first identified in 1973. It is present in plasma, saliva, and urine, and its plasma concentration decreases significantly with age, declining from approximately 200ng/mL at age 20 to 80ng/mL by age 60.
Research has established GHK-Cu as a potent inducer of tissue remodeling through its interaction with the copper chaperone Atox1 and activation of the SP1 transcription factor. It has been shown to modulate over 4,000 genes, with a particular focus on anti-inflammatory pathways.
Studies have demonstrated GHK-Cu's ability to stimulate collagen, elastin, glycosaminoglycan, and decorin synthesis while suppressing metalloproteinases responsible for collagen degradation. This dual action positions it as a compelling subject in regenerative medicine research.
Preclinical research has also examined GHK-Cu's effects on nerve regeneration, antioxidant gene activation (SOD1, SOD2, catalase), and its paradoxical ability to both stimulate and suppress specific growth factors depending on tissue type.
Research Use Only
For in vitro research and laboratory use only. Not approved by the TGA, FDA, or any regulatory authority for human or veterinary use. By purchasing, you confirm you are a qualified researcher using this compound solely for lawful scientific research.
